Life at Ensem
At Ensem, we are a passionate team focused on discovering transformative therapies for patients across the world. Our mission, values, people and strategy are essential in our ability to focus on traditionally undruggable targets. We are guided by our shared values.
We are One Ensem!
In addition to competitive salary and bonus, our many benefits include:
Generous Vacation
Medical, Dental and Vision Insurance
Life Insurance Long and short term disability
Cell/Internet Stipend
Employee Assistance Program
Paid Parental Leave
401(K) with 6% Company Match (no cap)
Employee referral program
Want to be a part of something special?
In joining our team you will feel the energy and passion of people truly working towards saving lives. We are building a first-class team dedicated to our Mission and excited to make the journey together. We work hard, but laugh more. We know you must enjoy the journey to be successful.
Open Positions
VP of Oncology Clinical Development
Ensem Therapeutics is seeking a VP and Head of Clinical Development. The successful candidate will be a highly motivated & results-driven individual with extensive oncology clinical development experience in biotech and/or pharma. S/he will work closely with preclinical Research team as well as external clinical consultants, drive the strategic planning and execution of first-in-human clinical trials through registrational studies.
· Review preclinical data and design first-in-human clinical trials for best- and/or first-in- class Oncology small molecules.
· Along with the project team, external consultants, and academic thought-leaders, the candidate will design clinical strategies to define proof-of-concept, as well as registration, and will execute on these strategies.
· Drive clinical study design, lead study protocol development, and collaborate with cross- functional teams and clinical investigators in all study activities.
· Oversee management of clinical trials, including investigator/site selection, patient recruitment strategies, milestones, and develop effective working relationships with clinical investigators, thought leaders, clinical consultants and CROs.
· Accountable for the preparation of Clinical Study Reports, Annual Reports and other safety reports, Health Authority pre-meeting packages, Investigator Brochures, and other periodic clinical reports.
· Direct, hands-on involvement in all aspects of clinical study conduct, including data review, analysis, and reporting that conforms to the highest ethical, safety, and quality standards and in compliance with regulatory standards.
· Manage internal and external resources to ensure clinical research plans are executed on time and within budget.
· Engage external business partner(s) and exert influence on joint clinical development strategy and study designs, with the goal of advancing ENSEM molecule from early clinical trials to final approval.
· Remain current on the therapeutic landscape in the relevant therapeutic areas in order to provide input and guidance for the strategic direction.
· Promote open, collaborative and entrepreneur culture.
· MD or MD PhD with board certification in the field of Medical Oncology.
· 5+ years of experience in the design, execution, and reporting of clinical trials in oncology preferably with small molecule drugs in pharmaceutical/biotech industry (or a combination of academia and industry).
· Excellent scientific knowledge relevant to clinical oncology, especially in the development of targeted therapies.
· In-depth knowledge of medical aspects of GCP, ICH, FDA, EMA, and other Country-specific guidelines and regulations for global submissions.
· Experience with U.S. and European Health Authority interactions and submission of clinical regulatory documents.
· Excellent leadership skills and proven ability to effectively work in a cross-functional/matrix environment and with contractors and CROs.
· Strong interpersonal, influencing, presentation, and written communication skills.
· Excellent organizational and time management skills. Dynamic, self-motivated, innovative, and critical thinker.
· Ability to travel to clinical trial sites, Conferences, Advisory Board meetings, etc.
Director Strategic Business Development
Ensem Therapeutics is seeking a Director Strategic Business Development. The successful candidate will be a results-driven & dynamic individual with extensive business development experience in biotech and/or pharma. S/he will conduct market analysis and work closely with ENSEM R&D team, to identify, evaluate and establish external collaborations to advance ENSEM’s home-grown programs.
· Participate in the development and execution of ENSEM corporate business strategy.
· Build strategic business proposal/recommendation to the Executive Management, with solid supporting data.
· Spearhead ENSEM business development from market forecasts, competitive intelligence analyses, valuations and scenario modeling, contract execution, detailed tracking of progress/status, to alliance management.
· Lead out-licensing (or in-licensing) business efforts for multiple products and indications, by championing term sheet negotiation and drafting agreements in close collaboration with internal teams, including R&D, legal, finance and others.
· Manage external interactions with partners and maintain dashboards on the health and progress of alliances, including tracking of development milestones and fulfillment of contractual obligations.
· Foster a culture of collaboration by developing and maintaining strong and positive relationships with stakeholders both internally and externally.
· MS/BS degree in life science or related field required, advanced degree in business or life science (MBA or Ph.D.) is preferred.
· 5+ yrs relevant experience in biotech/life sciences business development, alliance management, corporate development, due diligence, financial analysis, market and competitive research/analysis, and strategic planning.
· Strong communication and influencing skills, cross-functional team leadership abilities, as well as a high level understanding of drug discovery and development process.
· Experience in working with or in large multi-national pharma preferable, not required.
· Possesses a unique blend of strategic thinking, exceptional product and market expertise, and an ability to thrive in a startup environment.
Executive Administrative Assistant
Ensem Therapeutics is seeking an Executive Administrative Assistant. The Executive Admin will report to the President and Chief Executive Officer. In this role you will provide a high quality, comprehensive, accurate and timely administrative service. This role has responsibility for all logistical and administrative functions to ensure a professional interface, seamless communication, and optimal coordination of activities on their behalf.
· Manage calendars of the President and CEO and designated team members as required - responsible for meticulous calendar management, including planning meetings, coordinating recurring events and communicating with multiple parties to schedule large scale internal/external meetings.
· Arrange domestic and global travel for the team, including preparing relevant documentation and itinerary packages in a timely manner, manage real-time travel issues as they arise and preparing expense reports.
· Provide fluid support across both corporate and personal calendars including travel and appointments.
· Coordinate small and large meetings and events, both on and off-site, in collaboration with administrative staff from other locations, both domestic and international, as appropriate.
· Prepare and manage documents, drafting, editing and proofing various types of documents, including - memos, correspondence and non-technical presentation materials.
· Support internal team in Board of Director preparation.
· Follow-up actionable items arise from meetings e.g., producing minutes and ensuring timely distribution of relevant documents.
· Prepare, submit and tracking expense reports for the team, as necessary.
· Directs office activities and functions to maintain efficiency including telephone services, email correspondence, mail distribution and all office management needs (supplies, stocking, upkeep).
· Support organizing social and fun activities including Company lunches, off-site activities, etc.
· Maintains records, documentation, and files.
· Performs other related duties as assigned.
· Bachelors degree in Business, Communications or related field.
· Minimum of four years of experience as an administrative or equivalent supporting senior level executives.
· Proven experience as an EA within a similar industry (BioPharma, Med-Tech, etc.).
· Prior experience working with remote, international teams in a globally matrixed organization.
· Ability to represent the company and President and CEO in a professional manner.
· Excellent verbal and written communication skills, organizational skills and attention to detail.
· Excellent time management skills with a proven ability to meet deadlines and flexibility.
· Strong proficiency in Microsoft Office (Outlook, Word, PPT, etc.) and Microsoft Teams. Experience with Concur Function with the highest integrity.
· Ability to function well in a high-paced and at times stressful environment.